High frequency of IgE sensitization towards kiwi seed storage proteins among peanut allergic individuals also reporting allergy to kiwi
نویسندگان
چکیده
منابع مشابه
High frequency of IgE sensitization towards kiwi seed storage proteins among peanut allergic individuals also reporting allergy to kiwi
Background IgE sensitization to storage proteins from nuts and seed is often related to severe allergic symptoms. There is a risk of immunological IgE cross-reactivity between storage proteins from different species. The potential clinical implication of such cross-reactivity is that allergens other than the known sensitizer can cause allergic symptoms. Previous studies have suggested that kiwi...
متن کاملRelevance of IgE to novel kiwi seed allergens evaluated in kiwi allergic children
Background Kiwi fruit is a common food allergen and severe allergic reactions are observed. The current diagnostic accuracy is poor with a reported diagnostic sensitivity of 65% in a large European cohort. Recently, two new kiwi allergens were registered, both being storage proteins and both isolated from kiwi seeds. Storage proteins are often linked to severe clinical reactions in other food a...
متن کاملIgG and IgE avidity characteristics of peanut allergic individuals.
The role of antibody avidity in allergy is poorly understood and there is no existing literature describing antibody avidity in food allergy. The main aim of this study was to investigate IgE and IgG avidity to a total peanut protein extract (TPPE) and purified Ara h 2 in a group of well-characterized peanut allergic individuals. Forty peanut allergic patients underwent a double-blind placebo-c...
متن کاملIs peanut causing food allergy in Cuba? Preliminary assessment of allergic sensitization and IgE specificity profile to peanut allergens in Cuban allergic patients
BACKGROUND Peanut allergy is increasing at an alarming pace in developed countries. Peanut (Arachis hypogaea) is a common food in Cuba. Nevertheless, reported values of sensitization and symptom severity are usually low. As our objective, we carried out an evaluation of allergic sensitivity to perform an assessment of allergic sensitization and IgE specificity profile to peanut allergens in Cub...
متن کاملThe role of N-glycosylation in kiwi allergy
The physical, biochemical, and immunological characteristics of plant allergens have been widely studied, but no definite conclusion has been reached about what actually makes a protein an allergen. In this sense, N-glycosylation is an exclusive characteristic of plant allergens not present in mammals and it could be implied in allergenic sensitization. With this aim, we evaluated and compared ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Clinical and Molecular Allergy
سال: 2017
ISSN: 1476-7961
DOI: 10.1186/s12948-017-0073-4